Predictive value of Ki67 and p53 in locally advanced rectal cancer: Correlation with thymidylate synthase and histopathological tumor regression after neoadjuvant 5-FU-based chemoradiotherapy

Figure 1 Rectal adenocarcinomas with different tumor regression grade (TRG) after preoperative chemoradiotherapy: dominant tumor with obvious fibrosis in a non-responder, TRG1 (A); dominant fibrosis with very few tumor cell groups in a responder, TRG3 (B).