Predictive value of Ki67 and p53 in locally advanced rectal cancer: Correlation with thymidylate synthase and histopathological tumor regression after neoadjuvant 5-FU-based chemoradiotherapy

Table 3 Correlations in post-therapy resection specimens

Marker expression	Responders	Non-responders	P
TS < 0.881	26	2	< 0.01
TS ≥ 0.88	4	4
Ki67 < 40%	22	1	< 0.01
Ki67 ≥ 40%	7	6
p53 < 10%	10	3	0.98
p53 ≥ 10%	19	4

¹cut-off value.