Synthesis of platelet-activating factor and its receptor expression in Kupffer cells in rat carbon tetrachloride-induced cirrhosis

Figure 5 Competition binding assay (50 pmol/L ¹²⁵I-ET-1 ± 1 &mgr;mol/L unlabelled ET-1, 5 &mgr;mol/L ETA antagonist BQ-123 or 5 &mgr;mol/L ETB antagonist BQ-788). Specific binding of [¹²⁵I]-ET-1 was different in cell-associated radioactivity in the presence and absence of 1 &mgr;mol/L unlabelled ET-1. ^aP < 0.05, ^bP < 0.01 vs control; ^dP < 0.01 vs [¹²⁵I]-ET-1.