Outcome of patients with acute, necrotizing pancreatitis requiring drainage-does drainage size matter?

Table 1 Patient characteristics

Patient, n = 80	n/median (%/range)
Demographics
Age	57 (17-79)
Sex, female	26 (32.5)
Days of hospitalisation	51 (3-241)
Required second hospitalisation	5 (6.3)
Aetiology
Biliary	26 (32.5)
Alcoholic	32 (40.0)
Post-ERCP	3 (3.8)
Toxic	1 (1.3)
Hyperlipidemia	1 (1.3)
Hyperparathyroidism	1 (1.3)
Posttraumatic	1 (1.3)
Idiopathic/unknown	15 (18.8)
Ranson score	2 (0-4)
Diagnostic procedures
Ultrasound	74 (92.5)
ERCP	32 (40.0)
CT	80 (100)
Balthazar score	4 (3-4)
CTSI	6 (4-10)
Inflammatory markers
Leucocyte count d 1 of our hospital admission (/nL)	13 (3.5-55.0)
Leucocyte count on day of first drainage placement (/nL)	14.4 (3.5-46.6)
C-reactive protein day 1 (mg/L) of our hospital admission	208 (10-477)
C-reactive protein on day of first drainage placement (mg/L)	191 (20-477)
Therapy
Surgical	20 (25.0)
Minimal-invasive
Number of drainages, range	2 (1-14)
Active necrosectomy	18 (22.5)
Intensive care treatment	65 (81.3)
length of ICU stay, range	22 (2-104)
Required second ICU stays	9 (11.3)
APACHE II, range	18 (1-38)
SAPS II, range	61 (15-94)
Non-invasive positive pressure ventilation	2 (2.5)
Mechanical ventilation	50 (62.5)
Renal replacement therapy	23 (28.8)
Plasma exchange therapy	7 (8.8)
Mortality	27 (33.8)
Cause of Death
Septic multi-organe failure	24 (88.9)
Pulmonary embolism	1 (3.7)
Intracerebral bleeding	1 (3.7)
Due to polytrauma	1 (3.7)

ERCP: Endoscopic Retrograde Cholangiopancreatography; CT: Computed Tomography; CTSI: Computed Tomography Severity Index; ICU: Intensive Care Unit; APACHE: Acute Physiology and Chronic Health Evaluation; SAPS: Simplified Acute Physiology Scale.