Induction of IgA and sustained deficiency of cell proliferative response in chronic hepatitis C

Table 4 Correlation between demographic variables and aspects of humoral response

	Alcohol consumption	Specific treatment	Hepatic damage1
IgM2	R = -0.53b	R = 0.313	R = 0.107
	P = 0.01	P = 0.071	P = 0.609
IgA	R = -0.402a	R = 0.238	R = 0.422a
	P = 0.019	P = 0.176	P = 0.036
IgG3	R = -0.383a	R = 0.257	R = 0.100
	P = 0.028	P = 0.149	P = 0.635
IgG4	R = -0.717b	R = 0.418a	R = 0.401a
	P = 0.000	P = 0.014	P = 0.047

¹Necro-inflammatory activity;

²IgM positive response to HCV structural antigens;

³IgG positive response to HCV HVR-1 peptide; R = Spearman’s correlation coefficient;

^aSignificant correlation at 0.05 level;

^bSignificant correlation at 0.01 level.