Gene expression profiling: Canonical molecular changes and clinicopathological features in sporadic colorectal cancers

Figure 2 Pattern of expression of genes in the “antigen presentation, endogenous antigen” gene set as distinguished by tumor location and p53 status. Protein p53 alterations in the ascending colon coordinately decreased the expression of genes in the gene set whereas p53 alterations in the descending colon or rectum had no effect on gene expression. R: Cecum-splenic flexure of transverse colon; L: Splenic flexure of transverse colon-sigmoid colon; P: Rectum.