Gene expression profiling: Canonical molecular changes and clinicopathological features in sporadic colorectal cancers

Figure 1 Quantitative RT-PCR of selected genes associated with molecular changes and clinicopathological features from microarray gene expression data. These were NUDFC1 and SCL19A2 (with APC mutations), MT1X and MT1A (with MMR defects), SPRR3 (with crossover), CCL16 (with lymphovascular or neural invasion), and MRPL16 and MKKS (with synchronous adenoma). Genes differentially expressed between two groups were selected and their expression patterns measured using RT-PCR. WT: Without molecular or clinicopathological changes; MT: Molecular or clinicopathological changes. P-values from unpaired t-tests are shown.