Gene expression profiling: Canonical molecular changes and clinicopathological features in sporadic colorectal cancers

Table 1 Clinicopathological features relative to location of sporadic colorectal cancers

Clinicopathologic features	Tumor location1 (No. of patients)			P
	R (n = 27)	L (n = 29)	P (n = 28)
Male/Female	18/9	15/14	20/8	0.273
Age	62 ± 7	60 ± 12	62 ± 10	0.646
AJCC stage2, I/II/III/IV	4/13/6/4	4/15/6/4	4/10/9/5	0.926
Tumor differentiation, WD	22/5	29/0	24/4	0.021 (R vs L)
+ MD/PD + muc				0.052 (L vs P)
Synchronous adenoma, -/+	18/9	23/6	14/14	0.052 (L vs P)
LVN invasion, -/+	15/12	22/7	20/8	0.236

¹R: Cecum-splenic flexure of transverse colon; L: Splenic flexure of transverse colon-sigmoid colon; P: Rectum.

²According to the American Joint Committee on Cancer (6th ed., 2001). WD, MD, PD, and muc, well-, moderately-, poorly-differentiated, and mucinous. LVN: Lymphovascular or neural invasion of tumor cells.