Optical coherence tomography in detection of dysplasia and cancer of the gastrointestinal tract and bilio-pancreatic ductal system

Figure 6 Barrett’s esophagus (arrow). OCT features predictive for the presence of intestinal metaplasia are: The absence of the layered structure of the normal squamous epithelium and the presence of the vertical crypt-and-pit morphology of normal gastric mucosa; a disorganized architecture with inhomogeneous backscattering of the signal and an irregular mucosal surface; the presence of submucosal glands characterized by a markedly hypo-reflective tissue below the epithelial surface.