Different effects of ghrelin, des-acyl ghrelin and obestatin on gastroduodenal motility in conscious rats

Figure 2 Ghrelin and gastro-duodenal motility. A: Effects of iv injection of ghrelin on the fed motor activity of the antrum and duodenum. Iv injection of ghrelin induces the fasted pattern in the duodenum and increases the motor activity in the antrum; B: Iv injection of GHS-R antagonist completely blocks the effect of iv injection of ghrelin; C: Icv injection of NPY antiserum completely blocks the effect of iv injection of ghrelin; D: The density of c-Fos-positive cells in the arcuate nucleus (ARC) and nucleus tractus solitarius (NTS) increases with ip injection of ghrelin compared to saline-injected control.