Gardenia jasminoides protects against cerulein-induced acute pancreatitis

Figure 4 Effects of the GJ on pancreatic inflammatory changes following pancreatitis. A: Representative H&E-stained sections of pancreas in control mice (CON) who were not given cerulein, in mice given cerulein (CAE), and in mice given GJ (1 mg/kg) at the same time as the first cerulein injection; B: Histological sections of pancreas harvested 12 h after injection of saline (CON), cerulein alone, or GJ (1 or 0.1 mg/kg) given at the same time as the first injection of cerulein. The results were scored from 0 (normal) to 3 (severe) for edema, inflammation, vacuolization, and necrosis. ^aP < 0.05 vs saline treatment; ^bP < 0.05 vs cerulein treatment alone. The figure shows the results of one experiment in which 4-5 mice were tested per group. The results obtained were similar to those in three additional experiments (× 200).