Liver stiffness in the hepatitis B virus carrier: A non-invasive marker of liver disease influenced by the pattern of transaminases

Table 3 Factors associated with FS values at uni and multivariate analysis in 171 chronic HBV carriers

Variable		Univariate analysis	Multivariate analysis
		P	B	95% CI	P
Age	yr	0.006			NS
Sex	Male	0.002			NS
Phase of infection1	CHB	< 0.001	-9.939	-12.989-6.889	< 0.001
Alcohol introduction	> 60 g/d	0.076			NS
Diabetes	Present	NS
Hyperlipemia	Present	0.089			NS
BMI	> 25 kg/m2	< 0.001			NS
ALT	Log10 IU/mL	< 0.001	5.713	3.333-8.094	< 0.001
Biochemical remission2	Present	< 0.001			NS
HBV-DNA serum levels	Log10 IU/mL	0.051	-0.470	-0.924/-0.016	0.042
Disease stage3	Class	< 0.001	5.021	4.269-5.773	< 0.001

¹CHB patients vs inactive carriers;

²Biochemical remission means normal ALT ≥ 12 mo;

³Inactive carriers, CHB S0-S2, S3-S4, S5-S6, US cirrhosis. NS: No significance.