Gli-1 siRNA induced apoptosis in Huh7 cells

doi:10.3748/wjg.14.582

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Jan 28, 2008 (publication date) through Sep 26, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 28, 2008; 14(4): 582-589
Published online Jan 28, 2008. doi: 10.3748/wjg.14.582

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Figure 4 Effects of Gli-1 siRNA on Bcl-2 family member expressions in Huh7 cells. A: The expressions of Bcl-2 family member mRNA 24 h after transfection with Gli-1 siRNA analyzed by RT-PCR. The expression of Bcl-2 was remarkably decreased, but no change for other members; B: The protein of Bcl-2 was detected by Western blot. The Bcl-2 protein was markedly decreased after 24 h treatment with Gli-1 siRNA; C: Bcl-2 siRNA effectively inhibited the expressions of Bcl-2, but the mRNA of Gli-1 was no change after transfection with Bcl-2 siRNA.

Citation: Chen XL, Cao LQ, She MR, Wang Q, Huang XH, Fu XH. Gli-1 siRNA induced apoptosis in Huh7 cells. World J Gastroenterol 2008; 14(4): 582-589
URL: https://www.wjgnet.com/1007-9327/full/v14/i4/582.htm
DOI: https://dx.doi.org/10.3748/wjg.14.582