An effective vaccine against colon cancer in mice: Use of recombinant adenovirus interleukin-12 transduced dendritic cells

doi:10.3748/wjg.14.532

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Jan 28, 2008 (publication date) through Jan 17, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Colorectal Cancer

World J Gastroenterol. Jan 28, 2008; 14(4): 532-540
Published online Jan 28, 2008. doi: 10.3748/wjg.14.532

Table 1 Phenotypic characteristics of AdVIL-12/DCs

DCs¹	Mean fluorescence intensity
DCs¹	MHCI	MHCII	CD40	CD11b	CD11c	CD80	CD86	CD8α
Nontransduced	35	92	19	48	26	112	69	10
AdVIL-12	49	304^a	23	56	30	271^a	229^a	9

¹Nontransduced DCs and AdVIL-12 transduced DCs were harvested 6 d after the culture initiation and stained with the listed antibodies. Background intensities = 4-6.

^aP < 0.05 vs those of nontransduced DCs.

Citation: He XZ, Wang L, Zhang YY. An effective vaccine against colon cancer in mice: Use of recombinant adenovirus interleukin-12 transduced dendritic cells. World J Gastroenterol 2008; 14(4): 532-540
URL: https://www.wjgnet.com/1007-9327/full/v14/i4/532.htm
DOI: https://dx.doi.org/10.3748/wjg.14.532