Facilitating effects of berberine on rat pancreatic islets through modulating hepatic nuclear factor 4 alpha expression and glucokinase activity

Figure 3 Effects of berberine and GB on HNF4α mRNA expression. A: A representative gel electrophresis profile of DNA fragment; B: Semi-quantitative mRNA determination, results were normalized to β-actin and expressed as arbitrary unit. M: DNA Marker, control and GB represent islets of untreated and 1 μmol/L GB treated groups; 1, 3, 10 and 30 represent berberine groups of indicated concentrations. Data are presented as mean ± SD (n = 6), ^bP < 0.01 vs control.