Fibrinogen-like protein 2/fibroleukin prothrombinase contributes to tumor hypercoagulability via IL-2 and IFN-γ

Figure 2 Hfgl2 mRNA detection in human tumor tissues by in situ hybridization. A: Hfgl2 mRNA was stained purple in lung small cell carcinoma, hfgl2 mRNA present in the nests of tumor cells, some tumor cells secreted melanin (× 400); B: Submucosa of colon descendens tubular adenocarcinoma, hfgl2 mRNA present in the infiltrated cells and single migrating tumor cells (× 400); C: Invasive ductal breast carcinoma, hfgl2 mRNA localized to nest tumor cells, exfoliated tumor cells and infiltrated cells around the duct (× 400); D: Submucosa of gastric adenocarcinoma, hfgl2 mRNA localized to tumor blood vessel endothelium (× 400). Arrows indicate hfgl2 mRNA locations.