FR167653, a p38 mitogen-activated protein kinase inhibitor, aggravates experimental colitis in mice

Figure 1 Changes in body weight (A) and survival rate (B). Mice were fed DSS and injected intraperitoneally with vehicle (PBS) or FR167653 (30 mg/kg per day) daily starting at d 0. The weight of individual mice was followed daily. Data represent mean ± SE (n = 8 mice/group). ^aP < 0.05, FR167653 vs vehicle (PBS).