Evidence for the involvement of NOD2 in regulating colonic epithelial cell growth and survival

Figure 2 Decreased proliferation of NOD2-deficient CECs. Sections of colon from Nod2^+/+ (wild type: WT) and Nod2^-/- mice obtained prior to (0 h) and 24 h after enteric Salmonella infection were stained with an anti-Ki67 antibody and DAB and then counterstained with H&E. Ki67-reactive cells within the crypt regions are identified by the darkly stained nuclei. The arrows indicate the crypt-villous height with the scale bar representing 100 μm.