Depletion of CD4+CD25+ regulatory T cells can promote local immunity to suppress tumor growth in benzo[a]pyrene-induced forestomach carcinoma

Figure 6 CD4⁺CD25⁺ T cells in distinct microenvironments. Lymphocytes in RLNs (A), PLNs (B), spleen (C), and thymus (D) were double-stained with FITC-anti-CD25 and PE-anti-CD4 mAbs and quantified by flow cytometry in the control, BaP + IgG-treated, and BaP + PC61-treated mice at wk 7, wk 16, and wk 32. ^aP < 0.05, ^bP < 0.01, ^cP < 0.005, ^dP < 0.001 vs the control mice.