Choledochoscope manometry about different drugs on the Sphincter of Oddi

Table 3 Effects of protease inhibitor on SO pressure (mean ± SD)

		Ulinastatin 2500 U (n = 25)	Ulinastatin 5000 U (n = 25)	Gabexate mesilate (n = 25)
SOBP (mmHg)	Before administration	11.53 ± 4.22	11.81 ± 5.21	14.33 ± 3.74
	10 min	11.96 ± 7.91	9.16 ± 5.97	12.31 ± 4.15
	20 min	9.25 ± 4.43	8.70 ± 4.50a	11.61 ± 4.50b
SOCA (mmHg)	Before administration	78.63 ± 35.96	65.21 ± 23.46	94.84 ± 39.64
	10 min	64.79 ± 22.25	63.73 ± 33.52	90.60 ± 38.69
	20 min	53.35 ± 25.52c	47.13 ± 21.53d	80.55 ± 27.58
SOF (t/min)	Before administration	6.67 ± 2.15	7.38 ± 2.58	7.01 ± 1.57
	10 min	6.03 ± 2.10	5.29 ± 2.39e	6.45 ± 1.24
	20 min	5.57 ± 1.92	4.65 ± 2.47f	6.14 ± 1.73
CDBP (mmHg)	Before administration	7.34 ± 3.06	9.06 ± 4.50	9.68 ± 3.25
	10 min	8.03 ± 3.97	8.51 ± 5.41	10.87 ± 4.55
	20 min	7.47 ± 4.21	8.80 ± 3.50	11.07 ± 4.05

11.81 ± 5.21 vs 8.70 ± 4.50,

^aP < 0.05; 14.33 ± 3.74 vs 11.61 ± 4.50,

^bP < 0.05; 78.63 ± 35.96 vs 53.35 ± 25.52,

^cP < 0.01; 65.21 ± 23.46 vs 47.13 ± 21.53,

^dP < 0.01; 7.38 ± 2.58 vs 5.29 ± 2.39,

^eP < 0.01; 7.38 ± 2.58 vs 4.65 ± 2.47,

^fP < 0.01.