Depletion of CD4+CD25+ regulatory T cells can promote local immunity to suppress tumor growth in benzo[a]pyrene-induced forestomach carcinoma

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Oct 14, 2008 (publication date) through Nov 24, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Esophageal Cancer

World J Gastroenterol. Oct 14, 2008; 14(38): 5797-5809
Published online Oct 14, 2008. doi: 10.3748/wjg.14.5797

Table 2 Effects of depleted Tregs on tumor formation

	Time	BaP+IgG	BaP+PC61
Infiltrating cells	16 wk	-/+	+
	32 wk	-/+	+++
Apoptotic cells	16 wk	-	+
	32 wk	+	+++
Apoptosis occurred in tumor nodules	16 wk	-	+
Apoptosis occurred in tumor nodules	32 wk	-	+++

+++: Severe; ++: Moderate; +: Mild; -/+: Few; -: Not found.

Citation: Chen YL, Fang JH, Lai MD, Shan YS. Depletion of CD4⁺CD25⁺ regulatory T cells can promote local immunity to suppress tumor growth in benzo[a]pyrene-induced forestomach carcinoma. World J Gastroenterol 2008; 14(38): 5797-5809
URL: https://www.wjgnet.com/1007-9327/full/v14/i38/5797.htm
DOI: https://dx.doi.org/10.3748/wjg.14.5797