Gastrointestinal polyposis with esophageal polyposis is useful for early diagnosis of Cowden’s disease

Figure 1 Polyposis in the rectum. A: Colonoscopy showing multiple polyps in the terminal ileum, colon and rectum, which gave the macroscopic appearance of smooth lesions. Moreover, the size of all polyps was within 5 mm or smaller; B: Pathological appearance of multiple polyps with all biopsy specimens of these lesions showing epithelial hyperplasia. These specimens were diagnosed histopathologically as hyperplastic polyps (arrow).