Esophageal epithelial surface in patients with gastroesophageal reflux disease: An electron microscopic study

Figure 3 A: The intercellular spaces between the most superficially located squamous epithelial cells are shown. Each dot represents an individual case and horizontal lines show the median values. There was no statistically significant difference among the groups; B: The intercellular spaces between the most superficially located squamous epithelial cells were quantified using the NIH Image program. The proportion of intercellular space relative to total superficial area was determined in individuals with NERD and RE, and in asymptomatic healthy individuals. Each dot represents an individual case. Horizontal lines show the median values. There was no statistically significant difference among the groups; C: The regularity of the luminal cellular surface structure of the squamous cells was compared between normal individuals and patients with RE or NERD. There was no difference in the cellular surface structure between normal individuals and patients with RE or NERD. Each dot represents an individual case and horizontal lines show the median values.