Association between hepatocellular carcinoma and type 2 diabetes mellitus in Italy: Potential role of insulin

Table 3 Etiology in the 465 HCC patients and prevalence of DM2 [mean  ±  SD, n (%)]

Etiology	N° HCC (%)	Age (yr)	Prevalence of DM2 (%)
HBV	20 (4.3)	63.3 ± 10.31	3 (15.0)
HCV	177 (38.1)	71.5 ± 7.31	47 (26.6)2
Alcohol	141 (30.4)	66.7 ± 8.51	52 (36.9) 2
HBV + HCV	8 (1.7)	60.8 ± 12.81	2 (25.0)
HBV + alcohol	9 (1.9)	62.9 ± 9.31	2 (22.2)
HCV + alcohol	81 (17.4)	67.7 ± 9.31	27 (33.3)
HBV + HCV + alcohol	2 (0.4)	68.4 ± 10.3	0
Cryptogenetic	27 (5.8)	68.6 ± 9.3	11 (40.7)

¹HCV vs HBV + HCV, P < 0.001; HCV vs HBV, P < 0.001; HCV vs HBV + alcohol, P < 0.001; HCV vs HCV + alcohol; HCV vs alcohol, P < 0.001;

²HCV vs alcohol, P = 0.048.