Association between hepatocellular carcinoma and type 2 diabetes mellitus in Italy: Potential role of insulin

Table 1 Frequency of DM2 in HCC patients and in controls

	Number of subjects	DM2 absent (%)	DM2 present (%)	OR (95% CI)	P	RR
HCC	465	320 (68.8)	145 (31.2)	3.12 (2.22-4.43)	< 0.001	2.46
Controls	490	428 (87.3)	62 (12.7)
Males				3.14 (2.14-4.63)	< 0.001	2.45
HCC	364	246 (67.6)	118 (32.4)
Controls	385	334 (86.7)	51 (13.3)
Females				3.11 (1.38-7.4)	0.002	2.55
HCC	101	74 (73.3)	27 (26.7)
Controls	105	94 (89.5)	11 (10.5)

HCC: Hepatocellular carcinoma; DM2: Type 2 diabetes mellitus; OR: Odds ratio; CI: Confidence interval; RR: Relative risk.