Virologic characteristics of hepatitis B virus in patients infected via maternal-fetal transmission

Table 1 MHC-I binding predictions of 144-183 residue of HbcAg, processed by the SMM method

Allele	Position (aa)	Pep length	Sequence	IC50 (nm)1
HLA A*3101	148-157	10	VVRRRGRSPR	30.9
HLA A*3101	150-159	10	RRRGRSPRRR	13.7
HLA A*3101	157-166	10	RRRTPSPRRR	19.2
HLA A*3101	159-167	9	RTPSPRRRR	38.4
HLA A*3101	165-174	10	RRRSQSPRRR	19.2
HLA A*3101	166-175	10	RRSQSPRRRR	35.4
HLA A*3101	167-175	9	RSQSPRRRR	13.7
HLA A*3201	159-167	9	RTPSPRRRR	48.6
HLA A*6801	145-154	9	ETTVVRRRGR	23
HLA A*6801	146-154	9	TTVVRRRGR	22.3
HLA B*0702	162-170	9	SPRRRRSQS	21.3
HLA B*0702	170-178	9	SPRRRRSQS	21.3
HLA B*0702	155-163	9	SPRRRTPSP	40.4
HLA B*0801	162-170	9	SPRRRRSQS	39.5
HLA B*0801	170-178	9	SPRRRRSQS	39.5
HLA B*2705	150-159	10	RRRGRSPRRR	49.5
HLA B*2705	164-173	10	RRRRSQSPRR	14.7
HLA B*2705	166-175	10	RRSQSPRRRR	33.9

¹IC₅₀ (nM) < 50 was considered as high affinity. Only IC₅₀ (nM) has been shown in the Table.