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©2008 The WJG Press and Baishideng.
World J Gastroenterol. Sep 28, 2008; 14(36): 5549-5556
Published online Sep 28, 2008. doi: 10.3748/wjg.14.5549
Published online Sep 28, 2008. doi: 10.3748/wjg.14.5549
Table 5 Relationship between clinical pathological parameters and nm23H1 genetic instability in HCC
| Clinical pathological factors | Cases | MSI+ (%) | LOH+ (%) | nm23H1+ (%) | nm23H1 expression intensity (mean ± SD) |
| Differentiation degree | 48 | 6 (12.50) | 11 (22.92) | 27 (56.25) | 25.96 ± 2.53 |
| High differentiation | 15 | 3 (20.00) | 2 (13.33) | 10 (66.67) | 27.87 ± 2.83 |
| Middle differentiation | 20 | 2 (10.00) | 5 (25.00) | 12 (60.00) | 22.37 ± 2.35 |
| Low differentiation | 13 | 1 (7.70) | 4 (30.77) | 5 (38.46) | 22.58 ± 2.56 |
| Liver infiltration | |||||
| Positive | 15 | 0 (00.00) | 8 (53.33) | 6 (40.00) | 23.84 ± 2.43 |
| Negative | 33 | 6 (18.18) | 3 (9.09) | 21 (63.64) | 25.63 ± 2.63 |
| Lymph node metastasis | |||||
| Positive | 20 | 1 (5.00) | 9 (45.00) | 4 (20.00) | 21.67 ± 2.56 |
| Negative | 28 | 5 (17.86) | 2 (7.14) | 23 (82.14)1 | 28.56 ± 2.01 |
| TNM stage | |||||
| I+ II | 29 | 5 (17.24) | 1 (3.45) | 22 (75.86) | 25.58 ± 2.33 |
| III + IV | 19 | 1 (5.26) | 10 (52.63)2 | 5 (26.32)2 | 24.27 ± 2.27 |
- Citation: Yang YQ, Wu L, Chen JX, Sun JZ, Li M, Li DM, Lu HY, Su ZH, Lin XQ, Li JC. Relationship between nm23H1 genetic instability and clinical pathological characteristics in Chinese digestive system cancer patients. World J Gastroenterol 2008; 14(36): 5549-5556
- URL: https://www.wjgnet.com/1007-9327/full/v14/i36/5549.htm
- DOI: https://dx.doi.org/10.3748/wjg.14.5549