Relationship between nm23H1 genetic instability and clinical pathological characteristics in Chinese digestive system cancer patients

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Sep 28, 2008 (publication date) through Mar 6, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Gastric Cancer

World J Gastroenterol. Sep 28, 2008; 14(36): 5549-5556
Published online Sep 28, 2008. doi: 10.3748/wjg.14.5549

Table 2 Relationship between MSI, LOH and nm23H1 protein expression in different cancers of digestive system

Group	Positive frequency of nm23H1 protein % (n/n)
Group	Gastric cancer	Colon cancer	HCC	Gallbladder cancer
MSI positive	87.50 (7/8)	75.00 (6/8)	83.33 (5/6)	63.64 (7/11)
MSI negative	46.88 (15/32)¹	45.45 (10/22)	52.38 (22/42)	41.67 (15/36)
LOH positive	14.29 (1/7)	33.33 (2/6)	27.27 (3/11)	11.11 (1/9)
LOH negative	63.64 (21/33)²	58.33 (14/24)	64.86 (24/37)³	55.26 (21/38)⁴

¹P = 0.04 vs MSI positive group;

²P = 0.017,

³P = 0.027,

⁴P = 0.016 vs LOH positive group.

Citation: Yang YQ, Wu L, Chen JX, Sun JZ, Li M, Li DM, Lu HY, Su ZH, Lin XQ, Li JC. Relationship between nm23H1 genetic instability and clinical pathological characteristics in Chinese digestive system cancer patients. World J Gastroenterol 2008; 14(36): 5549-5556
URL: https://www.wjgnet.com/1007-9327/full/v14/i36/5549.htm
DOI: https://dx.doi.org/10.3748/wjg.14.5549