Polymorphisms of microsomal triglyceride transfer protein in different hepatitis B virus-infected patients

doi:10.3748/wjg.14.5454

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 21, 2008; 14(35): 5454-5460
Published online Sep 21, 2008. doi: 10.3748/wjg.14.5454

Table 3 Genotype distributions of MTP H297Q and MTP-493G/T n (%)

SNP	Genotype	Self-limited HBV infection (n = 316)	Chronic hepatitis B total (n = 316)	Chronic hepatitis B without family history (n = 195)	χ²test
					SLHBV vs CHB total		SLHBV vs CHB no FH
					Value	P	Value	P
MTP H297Q	CC	33 (10.4)	33 (10.4)	20 (10.3)	0.452	0.798	2.588	0.274
	CG	148 (46.8)	140 (44.3)	78 (40.0)
	GG	135 (42.8)	143 (45.3)	97 (49.7)
MTP-493G/T	GG	232 (73.4)	256 (81.0)	163 (83.6)	8.543	0.015	7.199	0.019¹
	GT	80 (25.3)	52 (16.5)	30 (15.4)
	TT	4 (1.3)	8 (2.5)	2 (1.0)

¹Fisher's exact test (2-Tail). SLHBV: Self-limited HBV infection group; CHB total: Chronic hepatitis B total group; CHB no FH: Chronic hepatitis B without chronic hepatitis B family history group.

Citation: Yang ZT, Zhang XX, Kong XF, Zhang DH, Zhang SY, Jiang JH, Gong QM, Jin GD, Lu ZM. Polymorphisms of microsomal triglyceride transfer protein in different hepatitis B virus-infected patients. World J Gastroenterol 2008; 14(35): 5454-5460
URL: https://www.wjgnet.com/1007-9327/full/v14/i35/5454.htm
DOI: https://dx.doi.org/10.3748/wjg.14.5454