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©2008 The WJG Press and Baishideng.
World J Gastroenterol. Aug 28, 2008; 14(32): 5078-5083
Published online Aug 28, 2008. doi: 10.3748/wjg.14.5078
Published online Aug 28, 2008. doi: 10.3748/wjg.14.5078
Table 6 Interaction between alcohol drinking and polymorphisms of the ALDH2 and ADH2 genes, and the odds ratio (OR) for colorectal cancer
Genotypes | Drinker | Controls | Cases | OR1 (95% CI) |
ALDH2 | ||||
A/A + A/G | No | 64 | 32 | 1.00 |
G/G | No | 60 | 41 | 1.36 (0.76-2.43) |
A/A + A/G | Yes | 35 | 27 | 1.39 (0.69-2.81) |
G/G | Yes | 63 | 90 | 2.70 (1.57-4.66) |
ADH2 | ||||
G/G + G/A | No | 65 | 34 | 1.00 |
A/A | No | 59 | 39 | 1.27 (0.71-2.26) |
G/G + G/A | Yes | 64 | 54 | 1.65 (0.94-2.91) |
A/A | Yes | 34 | 63 | 3.44 (1.84-6.42) |
- Citation: Gao CM, Takezaki T, Wu JZ, Zhang XM, Cao HX, Ding JH, Liu YT, Li SP, Cao J, Matsuo K, Hamajima N, Tajima K. Polymorphisms of alcohol dehydrogenase 2 and aldehyde dehydrogenase 2 and colorectal cancer risk in Chinese males. World J Gastroenterol 2008; 14(32): 5078-5083
- URL: https://www.wjgnet.com/1007-9327/full/v14/i32/5078.htm
- DOI: https://dx.doi.org/10.3748/wjg.14.5078