Polymorphisms of alcohol dehydrogenase 2 and aldehyde dehydrogenase 2 and colorectal cancer risk in Chinese males

doi:10.3748/wjg.14.5078

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Aug 28, 2008 (publication date) through Feb 8, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 28, 2008; 14(32): 5078-5083
Published online Aug 28, 2008. doi: 10.3748/wjg.14.5078

Table 4 Multivariant analysis of smoking, alcohol drinking, ALDH2 and ADH2 genotypes and risk of colorectal cancer

	OR¹	95% CI	χ²	P
ALDH2	1.62	1.06-2.47	5.0035	0.0253
ADH2	1.73	1.15-2.58	7.0548	0.0079
Smokers	0.97	0.63-1.50	0.0138	0.9063
Alcohol drinkers	1.95	1.27-2.98	9.3884	0.0022

¹Logistic regression model included age (continuous), smoking (nonsmokers, current + former), alcohol drinking (nondrinkers, current + former drinkers), ALDH2 (A/A+A/G, G/G) and ADH2 genotype (G/G + G/A, A/A).

Citation: Gao CM, Takezaki T, Wu JZ, Zhang XM, Cao HX, Ding JH, Liu YT, Li SP, Cao J, Matsuo K, Hamajima N, Tajima K. Polymorphisms of alcohol dehydrogenase 2 and aldehyde dehydrogenase 2 and colorectal cancer risk in Chinese males. World J Gastroenterol 2008; 14(32): 5078-5083
URL: https://www.wjgnet.com/1007-9327/full/v14/i32/5078.htm
DOI: https://dx.doi.org/10.3748/wjg.14.5078