Polymorphisms of alcohol dehydrogenase 2 and aldehyde dehydrogenase 2 and colorectal cancer risk in Chinese males

Table 2 Adjusted odds ratio (OR) and 95% confidence interval (CI) for colorectal cancer with reference to ALDH2 and ADH2 polymorphisms

	Controls n (%)	Cases n (%)	OR1 (95% CI)	OR2 (95% CI)
ALDH2 genotype
G/G	123 (55.41)	131 (68.95)	1.00	1.00
G/A	90 (40.54)	54 (28.42)	0.56 (0.37-0.86)	0.56 (0.37-0.86)
A/A	9 (4.05)	5 (2.63)	0.52 (0.15-1.76)	0.52 (0.17-1.60)
G/A + A/A	99 (44.59)	59 (31.05)	0.56 (0.37-0.86)	0.56 (0.37-0.84)
A/A + A/G	99 (44.59)	59 (31.05)	1.00	1.00
G/G	123 (55.41)	131 (68.95)	1.79 (1.19-2.68)	1.79 (1.19-2.69)
ADH2 genotype
A/A	93 (41.89)	102 (53.68)	1.00	1.00
A/G	109 (49.10)	73 (38.42)	0.61 (0.41-0.92)	0.62 (0.41-0.93)
G/G	20 (9.01)	15 (7.89)	0.68 (0.33-1.41)	0.68 (0.33-1.40)
A/G + G/G	129 (58.11)	88 (46.32)	0.62 (0.41-0.94)	0.63 (0.42-0.93)
G/G + G/A	129 (58.11)	88 (46.32)	1.00	1.00
A/A	93 (41.89)	102 (53.68)	1.61 (1.09-2.38)	1.60 (1.08-2.36)

¹Crude OR,

²OR was adjusted by age and smoking status.