Narrow-band imaging optical chromocolonoscopy: Advantages and limitations

Figure 4 NBI image of colorectal cancer. A: Conventional view of an IIa + IIc lesion, 12 mm in size, located in the transverse colon; B: NBI view shows a well demarcated area and meshed capillary vessels clearly visible characterized by thick diameter, branching and curtail irregularity; C: Magnifying NBI view additionally shows the presence of a nearly avascular or loose microvascular area due to histological desmoplastic changes in the stromal tissue, suggesting deep submucosal invasion; D: Histopathological analysis revealed an adenocarcinoma invading deeply into the submucosa (2500 μm) with lymphovascular invasion.