Editorial
Copyright ©2008 The WJG Press and Baishideng.
World J Gastroenterol. Aug 21, 2008; 14(31): 4849-4860
Published online Aug 21, 2008. doi: 10.3748/wjg.14.4849
Table 3 Selected traditional and novel factors associated with the increased risk of CMV disease after liver transplantation
Traditional factorsRecently identified factors
CMV D+/R- > CMV R+Toll-like receptor gene polymorphism
Allograft rejectionMannose binding lectin deficiency
High viral replicationChemokine and cytokine defects (IL-10, MCP-1, CCR5)
Mycophenolate mofetilDeficiency in CMV-specific CD4+ T cells
Muromonab-CD3Deficiency in CMV-specific CD8+ T cells
Anti-thymocyte globulinExpression of immune evasion genes
AlemtuzumabProgrammed cell death 1 expression
HHV-6
HHV-7
Renal insufficiency
Others1