Prevention of hepatotoxicity due to anti tuberculosis treatment: A novel integrative approach

Table 6 Effects of herbal formulation addition on disease outcome

Treatment outcome for ATT	Control	Trial	P
Number of sputum +ve case at start (%)	67/192 (35)	137/316 (43)	0.03
Number of sputum +ve case after 1-month of treatment (%)	10/67 (14.93)	4/137 (2.9)	0.0068
Poorly resolved parenchymal lesion (%)	9/152 (5.92)	2/258 (0.78)	0.0037
Failure to improve functional status (%)	19/192 (10)	6/316 (2)	0.00013
Treatment dropouts (%)	10/192 (5.2)	0	0.0001
Weight (kg)	39.17 ± 5.5	40.65 ± 6.22	0.0016
Hb (%)	10.92 ± 2.01	11.17 ± 1.97	0.176
ESR mm in 1st hour	45.96 ± 18.52	38.84 ± 22.37	0.0001

P calculated by χ² (categorical data) and two-sided Student’s t-test with Welch’s procedure (continuous data with unequal variance).