Correlation between expression and differentiation of endocan in colorectal cancer

Figure 3 The expression of endocan in colon and rectum tissues. A: RT-PCR analysis of endocan mRNA in colon and rectum tissues. Endocan mRNA was highly expressed in normal colon and rectum tissue and well and mid- differentiated colorectal cancer tissues, but was down regulated in poorly differentiated colorectal cancer tissues. Endocan expression (up) and β-actin expression (down). 1: 100 bp Marker; 2: Normal colon and rectum mucous membrane; 3: Well-differentiated differentiated colorectal cancer tissue; 4: Moderately colorectal cancer tissue; 5: Poorly differentiated colorectal cancer tissue. B: Expression of endocan by Western blot. Endocan was detected at high expression levels in normal colorectal and well-differentated tissues; Moreover, there was a down regulation in the poorly differentiated colorectal cancer tissues. Lane 1, 3, 5: Normal mocusa, well-differentiated tissues; lane 2, 4, 6: Poorly-differentiated tissues.