Lysophosphatidic acid induced nuclear translocation of nuclear factor-&kappa;B in Panc-1 cells by mobilizing cytosolic free calcium

doi:10.3748/wjg.14.4473

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Jul 28, 2008 (publication date) through Dec 24, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 28, 2008; 14(28): 4473-4479
Published online Jul 28, 2008. doi: 10.3748/wjg.14.4473

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Figure 3 Effect of LPA on cytosolic free calcium in Panc-1. LPA evoked cytosolic free calcium in concentration-dependent manner. PTX-treatment at a concentration of 100 ng/ml for overnight abolished 10 &mgr;mol/L LPA-induced mobilization of [Ca²⁺]_i. Pretreatment of U73122 (10 &mgr;mol/L) for 10 min also abolished LPA-induced mobilization of [Ca²⁺]_i. ^bP < 0.01.

Citation: Arita Y, Ito T, Oono T, Kawabe K, Hisano T, Takayanagi R. Lysophosphatidic acid induced nuclear translocation of nuclear factor-κB in Panc-1 cells by mobilizing cytosolic free calcium. World J Gastroenterol 2008; 14(28): 4473-4479
URL: https://www.wjgnet.com/1007-9327/full/v14/i28/4473.htm
DOI: https://dx.doi.org/10.3748/wjg.14.4473