Hepatocellular carcinoma: Defining the place of surgery in an era of organ shortage

Table 1 Recurrence and survival rates following surgical treatment for hepatocellular carcinoma

Treatment	Author	n	Recurrence (%)	5-yr survival (%)
Liver resection
	Ercolani (2003)[61]	224	54.4	42.0
	Sim (2003)[62]	81	NS	59.01
	Belghiti (2003)[63]	328	NS	37.0
	Bartlett (2007)[59]	53	47.0	42.6
	Nuzzo (2007)[64]	248	46.0	24.0
Deceased donor liver transplantation
	Mazzaferro (1996) (Milan criteria)[33]	48	8.0	75.42
	Jonas (2001) (Milan criteria)[65]	120	16.0	71.0
	Figueras (2001) (5 cm, localised)[66]	307	21.0	63.0
	Yao (2001) (UCSF criteria)[34]	70	11.4	75.2
	Decaens (2006)[36]
	Milan criteria	279	NS	60.0
	Beyond Milan, but within UCSF	44	NS	45.6
	Beyond UCSF and Milan criteria	145	NS	34.7
Living donor liver transplantation
	Todo (2007)[67]
	Milan criteria	137	1.4	79.41
	Extended criteria	172	22.2	60.0
	Hwang (2005)[68]
	Milan criteria	173	NS	88.0
	Extended criteria	64	NS	60.01
	Jonas (2007)[69]
	Milan criteria	8	NS	75.0
	Extended criteria	13	NS	62.0
	Kwon (2007)[70]
	Extended criteria	139	NS	79.9
	Sugawara (2007)[71]
	Extended criteria (5 nodules <5cm)	78	10.0	75.0
	Soejima (2007)[40]
	Milan criteria	16	0.0	100
	Unlimited criteria	44	18.2	74.01
Salvage liver transplantation
	Belghiti (2003)[55]	18	5.6	61.0
	Schwartz (2006)[19]	18	44.0	NS
	Hwang (2007)[54]	17	NS	NS

NS: Not stated; UCSF: University of California San Francisco.

¹3-year survival;

²4-year survival.