AIDS-associated plasmablastic lymphoma presenting as a poorly differentiated esophageal tumor: A diagnostic dilemma

Table 2 Differential diagnosis of PBL

Tumor subtype	Carcinoma	PBL	Common DLBCL	BL	Plasmacytoma
Tumor cell size	Large	Large	Large	Intermediate	Intermediate
CD20	-	- to ±	+	+	-
CD45	-	Variable	+	+	-
CD138	-	+	-	-	+
VS38c	-	+	- to ±	-	+
MUM1	-	+	-	-	+
EBV	-	+	-	+	-
HHV-8	-	Variable	-	-	-

PBL: Plasmablastic lymphoma; DLBCL: Diffuse large B cell lymphoma; BL: Burkitt’s lymphoma; CD: Cluster of differentiation; MUM-1: Multiple myeloma oncogene-1-protein; EBV: Epstein Barr virus; HHV-8, human Herpes Virus type-8; +: Expression of the antigen in the majority of cells; -: Absence of antigen expression; ±: Weak antigen expression.