Basic Research
Copyright ©2008 The WJG Press and Baishideng.
World J Gastroenterol. Jul 7, 2008; 14(25): 4028-4039
Published online Jul 7, 2008. doi: 10.3748/wjg.14.4028
Table 2 Criteria for microscopic grading of experimental chronic colitis
Histologic grading
Feature0123
Abnormalities of mucosal architectureNone (Normal)Mild or focal, not exceeding lamina propriaModerate, not exceeding the submucosaSevere & diffuse, exceeding the submucosa
Crypt abnormalitiesNoneMild atrophyModerate atrophy, Branched cryptsSevere atrophy, branched crypts, cryptitis, crypt abscess
Inflammatory cell infiltrationNormalScattered cellsModerate or confluent cellsMassive infiltration of cells
Vascular dilatationNormal blood vesselsMild dilatation (localized)Moderate dilatation of several blood vesselsSevere generalized dilatation of blood vessels
EdemaNoneLow level limited to villiIn the submucosaAll over the section
Mast cellsNormal scattered cellsThree cells clustered in submucosaClusters of > 3 cells in the submucosaClusters in submucosa and serosa