Killing of p53-deficient hepatoma cells by parvovirus H-1 and chemotherapeutics requires promyelocytic leukemia protein

Figure 5 Treatment of p53 different tumor cells with chemotherapeutic agents. The p53 different HepG2 cells were treated with various chemotherapeutic agents alone or combined with H-1 PV infection (MOI = 20 pfu/cell). H-1 PV- or mock-infected cells were seeded into 6-well plates, and 1 h after infection cultures were treated with chemotherapeutic agents as indicated. Apoptosis was measured on day 3 by FACScan analysis. Data given represent mean values of triplicates.