Killing of p53-deficient hepatoma cells by parvovirus H-1 and chemotherapeutics requires promyelocytic leukemia protein

Figure 2 A: Cytotoxicity and induction of apoptosis in H-1 PV-infected p53 different tumor cell line pairs. The early damage of tumor cells upon H-1 PV infection was measured with a standardized toxicity test via supernatant adenylate kinase (AK) concentration; B: Induction of apoptosis in H-1 PV-infected tumor cells is shown in histograms for annexin V (FL1-H) of Hep3B4P and HepG2 cells. Data are given as mean values of triplicates.