Adipokines and ghrelin in gastric cancer cachexia

Table 3 All biochemical parameters in blood in whole subjects are shown

	Healthy controls (n = 30)	Patients with gastric cancer		P-value (between groups) (ANOVA)
		Non-cachexia (n = 30)	Cachexia (n = 30)
Albumin (gr/dL)	4.2 ± 0.2	4.0 ± 0.5	2.9± 0.2a	0.03
CRP (mg/L)	5.95 ± 0.8	9.72 ± 4.3e	12.9 ± 2.2a	< 0.001
Prealbumin (ng/mL)	52.5 ± 8.3	49.2 ± 6.4	41.0 ± 12.3a	0.001
Fasting glucose (mg/dL)	102.7 ± 8.3	105.7 ± 13.7	114.3 ± 13.8a	0.005
Insulin (&mgr;IU/mL)	21.8 ± 9.0	24.4 ± 6.3	18.4 ± 6.0c	0.04
HOMA-IR	5.58 ± 2.55	6.58 ± 1.89	5.05 ±1.68	0.07
IGF-1 (pg/mL)	95.0 ± 30.1	63.1 ± 13.1e	43.8 ± 9.5a	< 0.001
Resistin (ng/mL)	18.1	43.4e	66.7a	< 0.001
Ghrelin (ng/ml)	1332 ± 620	1980 ± 913	2305 ± 818a	< 0.001
Adiponectin (&mgr;g/mL)	22.6 ± 12.4	27.8 ± 11.9	36.5 ± 15.0a	0.045
Leptin (pg/mL)	2810 ± 818	2623 ± 665	3405 ± 640	0.003

^aP < 0.05 vs healthy controls and non cachexia;

^cP < 0.05 vs non-cachexia;

^eP < 0.05 vs healthy controls.