Adipokines and ghrelin in gastric cancer cachexia

Table 1 Clinical characteristics of the subjects (n = 30)

	Healthy controls	Patients with gastric cancer		P value
		Non-cachexia	Cachexia
Age (mean ± SD)	56.4 ± 3.0	55.8 ± 13.3	63.6 ± 13.8	0.0011
Gender (%)				0.34423
Male	20 (67)	25 (84)	23 (77)
Female	10 (33)	5 (16)	7 (23)
Tumor stage (%)				0.0072
I	-	6 (20)	0
II	-	12 (40)	3 (10)
III	-	8 (25)	12 (40)
IV	-	4 (15)	15 (50)
Tumor differentiation				0.3472
Differentiated		26 (87)	23 (77)
Undifferentiated		4 (13)	7 (23)
Operability				0.3512
Operable/No operable	-	30/0	28/2
Localization (%)				0.3692
Cardia	-	3 (10)	2 (6)
Corpus	-	6 (20)	10 (34)
Fundus	-	3 (10)	0
Antrum		18 (60)	18 (60)
WHO performance status (%)				0.1082, < 0.0013
0	30 (100)	9 (30)	3 (10)
1	0	14 (45)	11 (36)
2	0	6 (20)	6 (20)
3	0	0	7 (24)
4	0	1 (5)	3 (10)
GPS				< 0.00123
0	30 (100)	18 (60)	1 (5)
1	0	12 (40)	17 (55)
2	0	0	12 (40)

¹Patients with gastric cancer vs healthy control (ANOVA);

²Cachexia vs non-cachexia (χ²);

³Cachexia and non-cachexia vs healthy control (χ²).