Replication of clinical hepatitis B virus isolate and its application for selecting antiviral agents for chronic hepatitis B patients

doi:10.3748/wjg.14.3490

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Jun 14, 2008 (publication date) through Nov 23, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Viral Hepatitis

World J Gastroenterol. Jun 14, 2008; 14(22): 3490-3496
Published online Jun 14, 2008. doi: 10.3748/wjg.14.3490

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Figure 5 Antiviral susceptibility of an HBV isolate cloned from a patient with lamivudine resistance. An HBV isolate amplified from the sera of patients failing in lamivudine therapy was cloned into the pHY106 vector and analyzed in vitro. Lane 1-4: transfected cells treated with 0.01, 0.1, 1 and 10 &mgr;mol/L of adefovir; Lane 5-8: transfected cells treated with 0.01, 0.1, 1 and 10 &mgr;mol/L of lamivudine.

Citation: Lu YP, Guo T, Wang BJ, Dong JH, Zhu JF, Liu Z, Lu MJ, Yang DL. Replication of clinical hepatitis B virus isolate and its application for selecting antiviral agents for chronic hepatitis B patients. World J Gastroenterol 2008; 14(22): 3490-3496
URL: https://www.wjgnet.com/1007-9327/full/v14/i22/3490.htm
DOI: https://dx.doi.org/10.3748/wjg.14.3490