Replication of clinical hepatitis B virus isolate and its application for selecting antiviral agents for chronic hepatitis B patients

doi:10.3748/wjg.14.3490

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Jun 14, 2008 (publication date) through Dec 24, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Viral Hepatitis

World J Gastroenterol. Jun 14, 2008; 14(22): 3490-3496
Published online Jun 14, 2008. doi: 10.3748/wjg.14.3490

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Figure 4 Analysis of intracellular replication of clinical HBV isolates. HBV isolates were cloned into the vector pHY106 and transfected into Huh2 cells. Seventy-two hours after transfection, intracellular replicative intermediates were isolated and analyzed by Southern blot. Double-stranded (DS) and single-stranded (SS) intermediates are indicated. Lane 1-8: eight replicons of clinical HBV isolates; Lane 9: pHY106 negative control.

Citation: Lu YP, Guo T, Wang BJ, Dong JH, Zhu JF, Liu Z, Lu MJ, Yang DL. Replication of clinical hepatitis B virus isolate and its application for selecting antiviral agents for chronic hepatitis B patients. World J Gastroenterol 2008; 14(22): 3490-3496
URL: https://www.wjgnet.com/1007-9327/full/v14/i22/3490.htm
DOI: https://dx.doi.org/10.3748/wjg.14.3490