Preparation of chitosan-polyaspartic acid-5-fluorouracil nanoparticles and its anti-carcinoma effect on tumor growth in nude mice

Table 2 The mean tumor volume (cm²) and inhibition rate of tumor growth (IR) in four groups

Groups	Before treatment	After treatment
		3 d	7 d	IR	10 d	IR	14 d	IR
NS	0.11 ± 0.03	0.19 ± 0.05	0.33 ± 0.10		0.62 ± 0.28		0.80 ± 0.23
5-Fu	0.12 ± 0.03	0.12 ± 0.04	0.24 ± 0.11	27.76%	0.31 ± 0.19	50.27%	0.33 ± 0.20	58.69%
CTS-Pasp	0.12 ± 0.03	0.19 ± 0.04	0.32 ± 0.10	2.80%	0.54 ± 0.10	13.49%	0.76 ± 0.26	5.58%
CTS-Pasp-5Fu	0.10 ± 0.01	0.11 ±0.04	0.13 ± 0.05	60.76%	0.19 ± 0.05	68.99%	0.23 ± 0.07	70.82%