Heterogeneity of colorectal adenomas, the serrated adenoma, and implications for screening and surveillance

Table 2 Comparison of SSA polyps and HP polyps

	SSA	HP
Location	Right colon	Rectosigmoid
Shape	Flat	Pedunculated or flat
Size	> 5 mm	< 5 mm
Cytologic dysplasia	Minimal	Absent
Basal crypt dilation	Yes	No
Horizontal crypts	Yes	No
Branched crypts	Yes	No
Basal crypt serration	Yes	No
Nuclear shape	Round to oval	Flat or low columnar
Cytoplasmic eosinophilia	Prominent	Not prominent

SSA: Sessile serrated adenoma; HP: Hyperplastic polyp. Adapted from Li and Burgart[11].