Etiopathogenesis of primary biliary cirrhosis

doi:10.3748/wjg.14.3328

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Jun 7, 2008 (publication date) through Nov 6, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jun 7, 2008; 14(21): 3328-3337
Published online Jun 7, 2008. doi: 10.3748/wjg.14.3328

Table 2 Mitochondrial and nuclear autoantigens in PBC

	Autoantigens
Mitochondrial antigens	E2 subunits of 2-OADC	PDC-E2
Mitochondrial antigens		OGDC-E2
		BCOADC-E2
	Pyruvate dehydrogenase	E3BP
	complex	PDC E1α
Nuclear antigens	Nuclear pore complex	gp210
Nuclear antigens		nucleoporin 62
	Multiple nuclear dots	Sp100
		PML
	Anticentromere

2-OADC: 2-oxo-acid dehydrogenase complex; PDC: Pyruvate dehydrogenase complex; OGDC: Oxoglutarate dehydrogenase complex; BCOADC: Branched chain 2-oxo-acid dehydrogenase complex; E3BP: Dihydrolipoamide dehydrogenase (E3)-binding protein.

Citation: Lleo A, Invernizzi P, Mackay IR, Prince H, Zhong RQ, Gershwin ME. Etiopathogenesis of primary biliary cirrhosis. World J Gastroenterol 2008; 14(21): 3328-3337
URL: https://www.wjgnet.com/1007-9327/full/v14/i21/3328.htm
DOI: https://dx.doi.org/10.3748/wjg.14.3328