Venous diethylene glycol poisoning in patients with preexisting severe liver disease in China

Table 1 Basic information concerning patients receiving venous diethylene glycol injections (n = 64)

Item	DEG-poisoned group (n = 15)	Non-DEG-poisoned group (n = 49)	Statistical value	P value
Male sex (%)	14 (93.3)	35 (71.4)	3.071	0.080
Age (yr)
Median	50	48	1.11	0.267
Range	33-76	5-72
DEG intake-ml
Median	24	36	0.27	0.787
Range	9-72	2.4-114
DEG concentration (%)
Median	6	6	0.713	0.476
Range	3-6	1.2-6
Alcoholics (%)	7 (46.7)	19 (38.8)	0.296	0.586
Diagnosis			11.691	0.039
TLD (%)	12 (80.0)	21 (42.9)	6.344	0.012
CH (%)	2 (13.3)	19 (38.8)		0.1122
Other (%)	1 (6.7)	9 (18.4)		0.2582
Diuretics (%)	12 (80.0)	16 (32.7)		0.0202
Complication
Ascites (%)	10 (66.7)	9 (18.4)		0.000
Renal disease2 (%)	5 (33.3)	3 (6.1)		0.0141
Serum checking
ALT (U/L)	180.9 ± 269.9	201.4 ± 284.3	0.251	0.804
TB (&mgr;mol/L)	359.2 ± 245	239.3 ± 221.5	1.767	0.082
BUN (mmol/L)	7.9 ± 3.8	4.3 ± 2.9	3.372	0.003
Creatinine (&mgr;mol/L)	94.2 ± 24.6	58.7 ± 22.6	5.141	0.000
Ca2+ (mmol/L)	2.37 ± 0.17	2.25 ± 0.21	2.157	0.035
Phosphonium (mmol/L)	0.72 ± 0.43	1.00 ± 0.33	2.574	0.013
WBC (109/L)	6.47 ± 2.08	6.00 ± 5.34	0.326	0.746
NEUT	0.716 ± 0.114	0.587 ± 0.153	3.003	0.004
RBC (1012/L)	3.03 ± 0.92	3.33 ± 0.79	1.208	0.232
Hemoglobin (g/L)	99.9 ± 25.6	106.6 ± 18.8	1.035	0.305
Platelet count (109/L)	106.9 ± 50.6	125.9 ± 73.3	0.293	0.354

TLD: Terminal liver disease, including severe hepatitis, liver cirrhosis, recurrence of post liver transplantation; ALT: alanine aminotransferase; CH: Chronic hepatitis; TB: total bilirubin; WBC: White blood cells; RBC: Red blood cells; NEUT: Ratio of neutral leucocyte; BUN: Blood urea nitrogen.

¹Fisher's exact test;

²Pre-existing renal diseases, including kidney stones, proliferative renal cysts and urinary tract infections. One case of renal carcinoma was observed in the non-poisoned group.